Now showing items 1-20 of 21

    • Echeverría, Francisca; Valenzuela, Rodrigo; Bustamante, Andrés; Álvarez, Daniela; Ortiz, Macarena; Soto Alarcón, Sandra; Muñóz, Patricio; Corbari, Alicia; Videla Cabrera, Luis (Hindawi, 2018)
      Pharmacological therapy for nonalcoholic fatty liver disease (NAFLD) is not approved at the present time. For this purpose, the effect of combined eicosapentaenoic acid (EPA; 50 mg/kg/day) modulating hepatic lipid metabolism ...
    • Pedrozo Cibils, Zully; Sánchez, G.; Torrealba, N.; Valenzuela, Rodrigo; Fernández, Carolina; Hidalgo Tapia, María Cecilia; Lavandero González, Sergio; Donoso Laurent, Paulina (ELSEVIER SCIENCE BV, 2010-03)
      Type-2 ryanodine receptors (RyR2) - the calcium release channels of cardiac sarcoplasmic reticulum - have a central role in cardiac excitation-contraction coupling. In the heart, ischemia/reperfusion causes a rapid and ...
    • Castro, Pablo; Mc-Nab, Pablo; Bittner, Alex; Greig, Douglas; Quintana, Juan Carlos; Chiong Lay, Mario; Díaz Araya, Guillermo; Valenzuela, Rodrigo; Vergara, I.; Corbalán, Ramón; Lavandero González, Sergio (ELSEVIER SCIENCE INC, 2005-02-01)
      Meeting Abstract
    • Videla Cabrera, Luis; Vargas, Romina; Valenzuela, Rodrigo; Muñoz, Patricio; Corbari, Alicia; Hernandez-Rodas, María C. (Churchill Livingstone, 2019)
      © 2018 Supplementation with omega-3 fatty acids or thyroid hormone (T3) exhibit negative effects on inflammatory reactions in experimental animals. The aim of this work was to assess the hypothesis that docosahexaenoic ...
    • Walton-Diaz, Annerleim; Vinay, José Ignacio; Barahona, Jaime; Daels, Pieter; González, Mariano; Hidalgo, Juan Pablo; Palma, Cristian; Díaz, Pablo; Domenech, Alfredo; Valenzuela, Rodrigo; Marchant, Fernando (Springer Netherlands, 2017)
      © 2016, Springer Science+Business Media Dordrecht.Introduction: Between 5 and 10% of patients undergoing percutaneous nephrolithotomy (PCNL) develop postoperative sepsis 1, 2. Strategies to prevent infectious complications ...
    • Wagner, Mary-Elizabeth; Valenzuela, Rodrigo; Vargas Valero, Tomás; Colet Lagrille, Melanie; Allanore, Antoine (Electrochemical Soc, 2016)
      Impurities and additives play a key role in copper electrodeposition, in particular in upstream processes such as electrowinning or electrorefining. One common impurity is iron, mostly present as iron species Fe(II) in ...
    • Copaja Soto, Miguel; Valenzuela, Rodrigo; Saldaña, Adiela; Ocaranza, María Paz; Jalil Milad, Jorge; Vio, Carlos; Lijnen, Paul; Ordenes, Gamaliel; Vivar Sánchez, Raúl; Lavandero González, Sergio; Díaz Araya, Guillermo (SAGE PUBLICATIONS LTD, 2008-09)
      Introduction. Isoproterenol treatment of Brown Norway Lewis rats (high and low plasma angiotersin-I-converting enzyme activity., respectively) results in similar cardiac hypertrophy but higher cardiac fibrosis in Brown ...
    • Sánchez, Catherine A.; Andahur, Eliana I.; Valenzuela, Rodrigo; Castellón Vera, Enrique; Fulla Ortiz, Juan; Ramos, Christian G.; Triviño, Juan C. (IMPACT JOURNALS LLC, 2015)
      The different prostate cancer (PCa) cell populations (bulk and cancer stem cells, CSCs) release exosomes that contain miRNAs that could modify the local or premetastatic niche. The analysis of the differential expression ...
    • Sánchez, Catherine A.; Andahur, Eliana I.; Valenzuela, Rodrigo; Castellon Vera, Enrique; Fulla, Juan A.; Ramos, Christian G.; Trivino, Juan C. (IMPACT JOURNALS LLC, 2016)
      The different prostate cancer (PCa) cell populations (bulk and cancer stem cells, CSCs) release exosomes that contain miRNAs that could modify the local or premetastatic niche. The analysis of the differential expression ...
    • Castillo, Viviana; Valenzuela, Rodrigo; Huidobro Alvarado, Christian; Contreras, Héctor R.; Castellón, Enrique A. (Spandidos, 2014)
      Cancer stem cells (CSCs) have the ability to self-renew and differentiate to give rise to heterogeneous phenotype of the tumor cells. It is believed that these cells are involved in metastasis, recurrence and therapy ...
    • Troncoso Cotal, Rodrigo; Moraga, Francisco; Chiong Lay, Mario; Roldán S., Juan; Bravo Méndez, Roberto; Valenzuela, Rodrigo; Díaz Araya, Guillermo; Campo Sfeir, Andrea Estefanía del; Sanhueza Muñoz, Carlos Joaquín; Rodríguez Villarroel, Andrea Elizabeth; Vukasovic Ramírez, José Luis; Mellado, Rose Marie; Greig, Douglas; Castro, Pablo; Lavandero González, Sergio (WILEY-BLACKWELL PUBLISHING, 2009-05)
      We investigated the clinical response of chronic heart failure patients with beta(2)- adrenergic receptor Gln(27)-> Glu polymorphism treated for 6 months with carvedilol, a alpha/beta-antagonist with antioxidant properties. ...
    • Silva, Cecilia; Loyola, Gloria; Valenzuela, Rodrigo; García-Huidobro, Tea; Monasterio Opazo, Octavio; Bronfman, Miguel (FEBS, 1999)
      Acyl-CoAs are present at high concentrations within the cell, yet are strongly buffered by specific binding proteins in order to maintain a low intracellular unbound acyl-CoA concentration, compatible with their metabolic ...
    • Illesca, Paola; Valenzuela, Rodrigo; Espinosa, Alejandra; Echeverría, Francisca; Soto Alarcón, Sandra A.; Ortiz, Macarena; Videla Cabrera, Luis (Elsevier Masson SAS, 2019)
      © 2018 The Authors Background: White adipose tissue (WAT) have a relevant metabolic and inflammatory function, in overweight or obesity conditions. In this regard, the WAT under over feeding nutrition present a significant ...
    • Ivanovic, Daniza M.; Valenzuela, Rodrigo; Almagià, Atilio; Barrera, Cynthia; Arancibia, Violeta; Larraín, Cristián; Silva, Claudio; Billeke, Pablo; Zamorano, Francisco; Villagrán, Francisca; Orellana, Yasna; Martínez, Víctor (Elsevier Inc., 2019)
      Objectives Scholastic achievement (SA) is a multifactorial problem that depends on factors related to the child, the child's family, and the educational system. The aim of this study was to quantify the relative impact ...
    • Lange, Soledad; Gonzalez, Ibeth; Pinto, Mauricio P.; Arce, Maximiliano; Valenzuela, Rodrigo; Aranda, Evelyn; Elliot, Matias; Alvarez, Marjorie; Henriquez, Soledad; Velasquez, Ethel V.; Orge, Felipe; Oliva, Barbara; Gonzalez, Pamela; Villalon, Manuel; Cautivo, Kelly M.; (Wiley-Liss Inc., 2014)
      Knockout models have shown that the coagulation system has a role in vascular development and angiogenesis. Herein, we report for the first time that zymogen FX and its active form (FXa) possess anti-angiogenic properties. ...
    • Espinosa, Alejandra; Campos, Cristian; Díaz Vegas, Alexis; Galgani Fuentes, José; Juretic Díaz, Nevenka Militza; Osorio Fuentealba, César; Bucarey, José L.; Tapia, Gladys; Valenzuela, Rodrigo; Contreras Ferrat, Ariel Eduardo; Llanos Vidal, Paola; Jaimovich Pérez, Enrique (2013)
      Insulin resistance is defined as a reduced ability of insulin to stimulate glucose utilization. C57BL/6 mice fed with a high-fat diet (HFD) are a model of insulin resistance. In skeletal muscle, hydrogen peroxide (H2O2) ...
    • Barrera, Cynthia; Valenzuela, Rodrigo; Rincón, Miguel Ángel; Espinosa, Alejandra; Echeverria, Francisca; Romero, Nalda; Gonzalez-Mañan, Daniel; Videla Cabrera, Luis (Elsevier Inc., 2018)
      © 2018 Elsevier Inc. Enhanced iron levels in liver are associated with oxidative stress development and damage with increased fat accumulation. The aim of this work was to assess the hypothesis that antioxidant-rich extra ...
    • Castellón, Enrique A.; Valenzuela, Rodrigo; Lillo, Jorge; Castillo, Viviana; Contreras, Héctor R.; Gallegos, Iván; Mercado, Alejandro; Huidobro, Christian (2012)
      Prostate cancer (PCa) is the most frequently diagnosed malignancy in men worldwide. Chemotherapy response is very poor and resistance to hormone-based treatments is frequent in advances stages. Recently, tumor-initiating ...
    • Valenzuela, Rodrigo; Espinosa, Alejandra; González Mañán, Daniel Alonso; D'Espessailles Tapia, Amanda; Fernández Arancibia, Virginia; Videla Cabrera, Luis; Tapia Opazo, Gladys (2012)
      Omega-3 (n-3) long-chain polyunsaturated fatty acids (n-3 LCPUFA) are associated with several physiological functions, suggesting that their administration may prevent non transmissible chronic diseases. Therefore, we ...